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In both prokaryotes and eukaryotes, it is presumed that at several points, unique
proteins of low molecular weight (̴
35, 000) binds specifically to one of the 2 strands.
The binding appears to relate to those regions of the duplex rich A- T base pairing which
has a lower energy of hydrogen bonding than G- C base pairs and thus more susceptible
to melting
In both prokaryotes and eukaryotes, it is presumed that at several points, unique proteins of low molecular weight (̴ 35, 000) binds specifically to one of the 2 strands. The binding appears to relate to those regions of the duplex rich A- T base pairing which has a lower energy of hydrogen bonding than G- C base pairs and thus more susceptible to melting
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